Is There A Less Expensive Substitute For Mometasone Furoate Spray

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Mometasone Furoate 50 micrograms/dose Nasal Spray, suspension is indicated for the treatment of nasal polyps in adults 18 years of age and older. 4.2 Posology and method of administration. After initial priming of the Mometasone Furoate nasal spray pump, each actuation delivers approximately 100 mg of mometasone furoate suspension, containing.

Mometasone Furoate - Overview

Mometasone furoate, marketed as a cream, lotion, ointment and nasal spray is a medication used in treating inflammatory conditions related to the skin and other parts of the body. People who need a prescription for mometasone furoate in any of its common forms can use Push Health to connect with a local medical provider who can prescribe Elocon cream, Nasonex or other versions of mometasone furoate when appropriate to do so.

What Is Mometasone Furoate Used For?

Mometasone furoate belongs to a class of medications known as medium potency synthetic corticosteroids. As this type of medication, mometasone furoate has antiinflammatory and vasoconstrictive effects when used in places like the skin. Mometasone can also reduce symptoms of itching at times. While mometasone furoate's mechanism of action is not fully understood, it may be related to activating proteins known as lipocortins which inhibit phospholipase A2, eventually blocking the production of inflammatory mediators such as leukotrienes and prostaglandins. As Elocon, mometasone is used to reduce itching and inflammation in dermatoses that are thought to be responsive to corticosteroids. As Nasonex nasal spray, mometasone is used in the treatment of rhinitis caused by seasonal allergies. Mometasone is also active in the medication Asmanex used in the management of asthma.

Mometasone - Dosage and Cost

Mometasone furoate itself is a white powder that dissolves poorly in water. It is important to note that mometasone furoate cream can cause systemic effects when applied topically. In the body, mometasone is broken down into different metabolites which are largely undetectable in the plasma. When administered intravenously, mometasone furoate demonstrates a half life of under six hours and excretion is primarily through the bile. When using mometasone cream, many medical providers will prescribe Elocon cream to be applied once daily to affected areas. Following intravenous administration, the effective plasma elimination half-life of mometasone furoate is 5.8 hours. Any absorbed drug is excreted as metabolites mostly via the bile, and to a limited extent, into the urine. Mometasone 0.1% cream is affordable, costing under $12 for one 15 gram tube at a number of pharmacies in the United States. Some insurance plans may cover the cost of mometasone furoate prescriptions. Additionally, one might be able to find Elocon coupons, Nasonex coupons, or other coupons for branded forms of mometasone furoate online or through the manufacturer. When supplied as Elocon cream 0.1%, the ointment is available in 15 gram and 45 gram tubes.

Can I Buy Mometasone Furoate Online?

Mometasone furoate is a prescription medication meaning that it requires a consultation with a medical provider in the United States before it can be dispensed by a pharmacy. As a result, one cannot just buy mometasone furoate online or get mometasone OTC. People who think they need a prescription for mometasone furoate, however, can use Push Health to connect with a medical provider who can prescribe mometasone cream, ointment or nasal spray when appropriate and safe to do so.

Mometasone Furoate - Side Effects

Before using mometasone furoate, it is important to discuss how the medication works with one's medical provider and pharmacist as it can cause side effects. Side effects that may result from mometasone furoate cream use include skin atrophy, irritation, burning and redness. When used as mometasone nasal spray, side effects include bloody nose, headaches, cough and viral infections. Systemic effects as they relate to impacting the hypothalamic-pituitary-adrenal (HPA) axis are always a consideration with steroid medications. Mometasone furoate and alcohol should not be used together. Anyone who has a known hypersensitivity to mometasone furoate should not use the medication.

More Mometasone Information

Last updated October 21, 2019. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions.

Flonase and Nasonex are both nasal sprays but is one stronger than the other?

Medically reviewed by Drugs.com Last updated on Nov 6, 2018.

The difference is Flonase is available over-the-counter (OTC) and Nasonex is prescription only. There is no difference in their effect or side effects.

Flonase and Nasonex are both corticosteroid nasal sprays that are effective at treating hay fever, perennial allergic rhinitis and allergies. Nasonex is also FDA approved to treat nasal polyps. Flonase contains fluticasone and Nasonex contains mometasone; these are both glucocorticoid corticosteroids that help to relieve congestion, sneezing, postnasal drip, and other allergy symptoms, including eye symptoms.

Only Flonase is available OTC

Flonase is available over-the-counter, at the same strength as its prescription counterpart. At the time of writing (Sept 2016), Nasonex was only available by prescription. Both provide 24-hour relief of allergic rhinitis symptoms that is free from drowsiness. Regardless of which one you use it will take several hours before you feel any effects from the spray, and several days of regular use before the full effect is seen. This is why experts recommend you use a corticosteroid nasal spray from the start of the allergy season until the end, not just when you get a flare up of symptoms, in order to get the best results.

Flonase Vs Nasonex: Effectiveness and Side Effects

Several trials have shown that both fluticasone (Flonase) and mometasone (Nasonex) nasal sprays are equally effective, safe, and well tolerated for the treatment of allergic rhinitis.

Side effects caused by Flonase and Nasonex are similar and include a headache; stinging, burning or bleeding in the nose; a sore throat and watery eyes. The American Academy of Asthma, Allergy and Immunology (AAAI) warns that fluticasone nasal sprays (Flonase) do slow growth rate in children; one large study of 474 children reported an average slowing of 0.27 cm/year (as much as 0.48 cm and as little as 0.06 cm). While other studies that investigated mometasone (Nasonex) did not find it slowed growth rate, it is likely that numbers of participants in these trials were too few to show a difference. All children receiving intranasal corticosteroids for longer than two months should be monitored for any slowing of growth rate.

Flonase Vs Nasonex: Formulations

Flonase Allergy Relief delivers 0.05mg (50 microgram) fluticasone per spray. Children's Flonase Allergy relief also delivers 0.05mg (50 micrograms) fluticasone per spray - the same dose, but there are fewer sprays per bottle so it is less expensive. Neither the Flonase Allergy Relief nor the Children's Flonase Allergy relief should be used in children under the age of four. However, Flonase Sensimist Allergy Relief which delivers 0.0275mg (27.5microgram) fluticasone per spray may be used in children aged two to four.

Nasonex Nasal Spray has one strength, 0.05mg (50 micrograms) mometasone per spray and can be used by adults and children over the age of two. Windows 10 services safe to disable.

Bottom Line

In summary, choice of either Flonase or Nasonex comes down to personal preference, availability (only Flonase is available OTC) or price, as there is no difference in their effect or side effects. Both Flonase and Nasonex are available as generics.

See also:

References
  1. Nasonex Nasal Spray (mometasone nasal) [Package Insert] Apotex. Revised 02/2016. https://www.drugs.com/nasonex.html
  2. Flonase Nasal Spray (fluticasone propionate) Revised 10/2011 GlaxoSmithKline LLC https://www.drugs.com/pro/flonase.html
  3. Aneeza WH, Husain S, Rahman RA, Van Dort D, Abdullah A, Gendeh BS. Efficacy of mometasone furoate and fluticasone furoate on persistent allergic rhinoconjunctivitis. Allergy & Rhinology. 2013;4(3):e120-e126. doi:10.2500/ar.2013.4.0065.
  4. Mandl M, Nolop K, Lutsky BN. Comparison of once daily mometasone furoate (Nasonex) and fluticasone propionate aqueous nasal sprays for the treatment of perennial rhinitis. 194-079 Study Group. Ann Allergy Asthma Immunol. 1997 Oct;79(4):370-8.
  5. Kaiser HB, Liao Y, Diener P, et al. Triamcinolone acetonide and fluticasone propionate nasal sprays provide comparable relief of seasonal allergic rhinitis symptoms regardless of disease severity. Allergy Asthma Proc. 2004 Nov-Dec;25(6):423-8. http://www.ncbi.nlm.nih.gov/pubmed/15709453

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